How it Works

• Supports Cardiovascular and Neurologic Health
• Supports Homocysteine Balance
• Supports Healthy Arterial Function
• Maintains Normal Inflammatory Balance

Methylation is a vitamin-requiring biochemical process in the body that is critical for maintaining mental and physical health. Methylation helps convert the problematic amino acid metabolite homocysteine into the amino acids methionine and cysteine. Consistent recycling of homocysteine is vital for supporting cardiovascular health. Proper methylation can be inhibited by nutrient deficiencies, especially of folic acid, B₆ and B₁₂. Certain medication such as acetaminophen, aspirin, ibuprofen and oral contraceptives can also deplete blood levels of these crucial B vitamins, reducing the body's vital methylation capacity.

Cardio B contains targeted amounts of folic acid, B₁₂, B₆ and betaine (trimethylglycine) to support methylation pathways in the body.

Suggested Use:

1 or more capsules per day or as recommended by your health care professional.

Folate

Adequate folate status is critical for maintaining optimal methylation, red blood cell balance, DNA and RNA synthesis and healthy cell division and replication. Folic acid is converted into its metabolically active form, 5-MTHF, by the enzyme methylenetetrahydrofolate reductase (5-MTHFR). 5-MTHF donates its methyl group to vitamin B₁₂ (cobalamin), forming methylcobalamin. Methylcobalamin helps convert the problematic amino acid metabolite homocysteine into the amino acid methionine.

B₁₂

Vitamin B₁₂ (methylcobalamin) works along with folic acid in many body processes, including the synthesis of DNA, red blood cells and supporting health of the myelin sheath, the insulating exterior that surrounds nerve cells. B₁₂ is found primarily in animal foods. Vegetarians and the elderly are at highest risk for B₁₂ deficiency. B₁₂ is considered by many to be a vital nutrient required to balance homocysteine levels. Methylcobalamin is the biologically active form of B12 and supports up-regulation of methylation pathways.

B₆

Vitamin B₆ (pyridoxine) is a B vitamin that is required for more than 60 different enzymatic reactions that occur in the body. Vitamin B₆ works along with folic acid and B₁₂ for in the recycling of homocysteine. B₆ also supports a healthy cardiovascular system by promoting healthy platelet aggregation and aids in maintaining healthy blood pressure. Vitamin B₆ is required for the activation of lysyl oxidase, an enzyme responsible for the cross-linking of collagen, and elastin, which is crucial for maintaining normal circulation and arterial function.

Trimethylglycine (Betaine)

Trimethylglycine (betaine) functions in the body as a unique methyl donor, supporting liver function and detoxification pathways and the conversion of homocysteine to methionine. Trimethylglycine also works alongside B₆, B₁₂ and folic acid in supporting homocysteine balance.

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