Contains a blend of ingredients involved in mood and reduce stress*

Key ingredients:
Taurine: Neuroprotective amino acid that provides antioxidant protection and demonstrates GABA-A agonist activity (1-3).*

GABA is the primary inhibitory neurotransmitter in the brain important for calm and sleep (4-6).

L-theanine: In a randomized, double-blind, placebo-controlled study, L-theanine was shown to significantly reduce stress (7)(8).*

Precursors to serotonin and melatonin (from Griffonia simplicifolia seed extract) (9).* Serotonin is important for regulating mood and sleep-wake function (10). In a randomized, double-blind study, those precursors were shown to significantly improve mood (11).*

Vitamins B and C: Active forms of vitamin B6, folate, B12, and C are important for serotonin synthesis (12-16).*

References:

1. Kumari N, et al. Adv Exp Med Biol. 2013;775:19-27.
2. Shimada K, et al. Adv Exp Med Biol. 2015;803:581-96.
3. Kletke O, et al. PLoS One. 2013;8(4):e61733.
4. Gou Z, et al. Dongwuxue Yanjiu. 2012;33(E5-6):E75-81.
5. Mohler H. Neuropharmacology. 2012;62(1):42-53.
6. Saper C, et al. Nature. 2005;437(7063):1257-63.
7. Kakuda T, et al. Biosci Biotechnol Biochem. 2002;66(12):2683-2686.
8. Kimura K, et al. Biol Psychol. 2007; 74(1):39-45.
9. Shaw K, et al. Cochrane Database Syst Rev. 2002;(1):CD003198.
10. Monti J. Sleep Med Rev. 2011;15(4):269-81.
11. Jangid P, et al. Asian J Psychiatr. 2013;6(1):29-34.
12. Dakshinamurti K, et al. Ann N Y Acad Sci. 1990;585:128-44.
13. Bottiglieri T. Psychiatr Clin North Am. 2013;36(1):1-13.

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These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.