Combination of two uniquely designed blends of shelf-stable probiotics important for the gut-brain axis, improvement of mood, neurotransmitter synthesis, and balancing the immune response*

Key ingredients: ProBlend is a blend important for general gut health and immune response(1,2).* Lactobacilli as a species have been found to demonstrate immunomodulatory effects through natural detoxification and balancing the metabolism(3,4).* Lactobacillus rhamnosus (GG), one of the most studied probiotic strains in the world, demonstrates protective effects of epithelial barrier function against an unbalanced microbiota both in vitro and in vivo(5,6).* NeuroBlend is a blend important for neurotransmitter synthesis(3-6).* In a double-blind, placebocontrolled study, B. longum (Rosell®-175) and L. helveticus (Rosell®-52) significantly improved mood and median cortisol levels(1).* Lactobacillus brevis demonstrated the most efficient GABA production compared to 91 other strains(2).*

References
1. Messaoudi M, et al. Br J Nutr. 2011;105(5):755-64.
2. Barrett E, et al. J Appl Microbiol. 2012;113(2):411-7.
3. Di Cerbo A, et al. J Clin Pathol. 2016;69(3):187-203.
4. Cai S, et al. J Immunol Res. 2016;2016:7402760.
5. Johnson-Henry K, et al. Infect Immun. 2008;76(4):1340-8.
6. Mao X, et al. PLoS One. 2016;11(1):e0146312.

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These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.